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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUOX1 All Species: 29.39
Human Site: Y1041 Identified Species: 58.79
UniProt: Q9NRD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRD9 NP_787954.1 1551 177235 Y1041 F K R F I E N Y R R H I G C V
Chimpanzee Pan troglodytes XP_001163196 1551 177072 Y1041 F K R F I E N Y R R H I G C V
Rhesus Macaque Macaca mulatta XP_001111340 1551 176921 Y1041 F K R F I E N Y R R H I G C V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001092767 1551 177113 Y1041 F K R F I E N Y R R H I G C V
Rat Rattus norvegicus Q8CIY2 1551 177179 Y1041 F K R F I E N Y R R H I G C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518643 1547 175433 Y1037 F K R F V E N Y R R H I V C V
Chicken Gallus gallus XP_425053 1523 173782 Y1013 F K R F I E N Y R R H I V C V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919394 1322 150039 G831 V I V I F M T G T S E E K S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQH2 1475 170768 N964 Y I T F L E E N R Q N I F Y L
Honey Bee Apis mellifera XP_624355 1492 172466 N980 I S T F L E E N R Q N I F Y L
Nematode Worm Caenorhab. elegans O61213 1497 170397 Y984 V S A F L E T Y R Q H V F I V
Sea Urchin Strong. purpuratus NP_001118237 1671 189876 N1164 V V R F F E N N R L Q I F Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.7 N.A. N.A. 91 90.1 N.A. 73.9 65.1 N.A. 47.1 N.A. 39.9 40.3 34.3 41.6
Protein Similarity: 100 99.4 97.8 N.A. N.A. 95 94.4 N.A. 84.4 78.4 N.A. 61.7 N.A. 58 60.2 55.9 59.3
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 86.6 93.3 N.A. 0 N.A. 26.6 26.6 40 46.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 93.3 93.3 N.A. 0 N.A. 60 53.3 60 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 92 17 0 0 0 9 9 0 0 0 % E
% Phe: 59 0 0 92 17 0 0 0 0 0 0 0 34 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 42 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % H
% Ile: 9 17 0 9 50 0 0 0 0 0 0 84 0 9 0 % I
% Lys: 0 59 0 0 0 0 0 0 0 0 0 0 9 0 9 % K
% Leu: 0 0 0 0 25 0 0 0 0 9 0 0 0 0 17 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 67 25 0 0 17 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 25 9 0 0 0 0 % Q
% Arg: 0 0 67 0 0 0 0 0 92 59 0 0 0 0 0 % R
% Ser: 0 17 0 0 0 0 0 0 0 9 0 0 0 9 0 % S
% Thr: 0 0 17 0 0 0 17 0 9 0 0 0 0 0 0 % T
% Val: 25 9 9 0 9 0 0 0 0 0 0 9 17 0 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 67 0 0 0 0 0 25 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _